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From conversion to aggregation: Protofibril formation of the prion protein
The ability to diagnose and treat prion diseases is limited by our current understanding of the conversion process of the protein from healthy to harmful isoform. Whereas the monomeric, benign species is well characterized, the misfolded conformations responsible for infectivity and neurodegeneratio...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC356944/ https://ncbi.nlm.nih.gov/pubmed/14983003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307178101 |
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