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Cytoskeleton-dependent clustering of membrane-bound prion protein on the cell surface

Prion diseases are a group of neurodegenerative disorders that infect animals and humans with proteinaceous particles called prions. Prions consist of scrapie prion protein (PrP(Sc)), a misfolded version of the cellular prion protein (PrP(C)). During disease progression, PrP(Sc) replicates by intera...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hackl, Stefanie, Ng, Xue Wen, Lu, Danqin, Wohland, Thorsten, Becker, Christian F.W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988330/
https://ncbi.nlm.nih.gov/pubmed/33539927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100359
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