Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA

Interstrand cross-links are exceptionally bioactive DNA lesions. Endogenous generation of interstrand cross-links in genomic DNA may contribute to aging, neurodegeneration, and cancer. Abasic (Ap) sites are common lesions in genomic DNA that readily undergo spontaneous and amine-catalyzed strand cle...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Yang, Zhiyu, Price, Nathan E., Johnson, Kevin M., Wang, Yinsheng, Gates, Kent S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Chemical Biology and Nucleic Acid Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499897/
https://ncbi.nlm.nih.gov/pubmed/28531327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx394
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