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Chemical Structure and Properties of Interstrand Cross-Links Formed by Reaction of Guanine Residues with Abasic Sites in Duplex DNA

A new type of interstrand cross-link resulting from the reaction of a DNA abasic site with a guanine residue on the opposing strand of the double helix was recently identified, but the chemical connectivity of the cross-link was not rigorously established. The work described here was designed to cha...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Catalano, Michael J., Liu, Shuo, Andersen, Nisana, Yang, Zhiyu, Johnson, Kevin M., Price, Nathan E., Wang, Yinsheng, Gates, Kent S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706233/
https://ncbi.nlm.nih.gov/pubmed/25710271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b00669
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