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Interstrand DNA–DNA Cross-Link Formation Between Adenine Residues and Abasic Sites in Duplex DNA
[Image: see text] The loss of a coding nucleobase from the structure of DNA is a common event that generates an abasic (Ap) site (1). Ap sites exist as an equilibrating mixture of a cyclic hemiacetal and a ring-opened aldehyde. Aldehydes are electrophilic functional groups that can form covalent add...
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| Główni autorzy: | , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2014
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954461/ https://ncbi.nlm.nih.gov/pubmed/24506784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410969x |
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