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Chemical and structural characterization of interstrand cross-links formed between abasic sites and adenine residues in duplex DNA

A new type of interstrand DNA–DNA cross-link between abasic (Ap) sites and 2′-deoxyadenosine (dA) residues was recently reported, but the chemical structure and properties of this lesion were not rigorously established. Here we characterized the nucleoside cross-link remnant released by enzymatic di...

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Publicat a:Nucleic Acids Res
Autors principals: Price, Nathan E., Catalano, Michael J., Liu, Shuo, Wang, Yinsheng, Gates, Kent S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402519/
https://ncbi.nlm.nih.gov/pubmed/25779045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv174
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