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Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells
Apurinic/apyrimidinic (AP) sites, or abasic sites, which are a common type of endogenous DNA damage, can forge interstrand DNA–DNA cross-links via reaction with the exocyclic amino group on a nearby 2΄-deoxyguanosine or 2΄-deoxyadenosine in the opposite strand. Here, we utilized a shuttle vector met...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499640/ https://ncbi.nlm.nih.gov/pubmed/28431012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx266 |
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