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A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites

Interstrand DNA-DNA cross-links are highly toxic lesions that are important in medicinal chemistry, toxicology, and endogenous biology. In current models of replication-dependent repair, stalling of a replication fork activates the Fanconi anemia pathway and cross-links are “unhooked” by the action...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:DNA Repair (Amst)
Hauptverfasser: Yang, Zhiyu, Nejad, Maryam Imani, Varela, Jacqueline Gamboa, Price, Nathan, Wang, Yinsheng, Gates, Kent S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424475/
https://ncbi.nlm.nih.gov/pubmed/28262582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.02.011
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