Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner

Cytosine modifications diversify and structure the genome thereby controlling proper development and differentiation. Here, we focus on the interplay of the 5-methylcytosine reader Mbd1 and modifier Tet1 by analyzing their dynamic subcellular localization and the formation of the Tet oxidation produ...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Zhang, Peng, Rausch, Cathia, Hastert, Florian D., Boneva, Boyana, Filatova, Alina, Patil, Sujit J., Nuber, Ulrike A., Gao, Yu, Zhao, Xinyu, Cardoso, M. Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499542/
https://ncbi.nlm.nih.gov/pubmed/28449087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx281
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