Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours

Inhibitory interneurons in the spinal dorsal horn (SDH) are crucial for processing somatosensory information originating in the periphery. However, the effects of the acute and selective inactivation of GABAergic SDH interneurons on pain processing are not fully understood. In this study, we used de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Koga, Keisuke, Kanehisa, Kensho, Kohro, Yuta, Shiratori-Hayashi, Miho, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide, Furue, Hidemasa, Tsuda, Makoto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498492/
https://ncbi.nlm.nih.gov/pubmed/28680103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04972-3
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