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Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa
Exophilin-8 has been reported to play a role in anchoring secretory granules within the actin cortex, due to its direct binding activities to Rab27 on the granule membrane and to F-actin and its motor protein, myosin-Va. Here, we show that exophilin-8 accumulates granules in the cortical F-actin net...
Shranjeno v:
| izdano v: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496739/ https://ncbi.nlm.nih.gov/pubmed/28673385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26174 |
| Oznake: |
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