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Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin
Before undergoing neuroexocytosis, secretory granules (SGs) are mobilized and tethered to the cortical actin network by an unknown mechanism. Using an SG pull-down assay and mass spectrometry, we found that myosin VI was recruited to SGs in a Ca(2+)-dependent manner. Interfering with myosin VI funct...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563687/ https://ncbi.nlm.nih.gov/pubmed/23382463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201204092 |
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