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Granuphilin Modulates the Exocytosis of Secretory Granules through Interaction with Syntaxin 1a

The molecular mechanism for the regulated exocytosis of dense-core granules in endocrine cells remains relatively uncharacterized compared to that of synaptic vesicles in neurons. A novel set of Rab and its effector, Rab27a/granuphilin, which is localized on insulin granules in pancreatic beta cells...

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Detalhes bibliográficos
Main Authors: Torii, Seiji, Zhao, Shengli, Yi, Zhaohong, Takeuchi, Toshiyuki, Izumi, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133943/
https://ncbi.nlm.nih.gov/pubmed/12101244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5518-5526.2002
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