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Granuphilin exclusively mediates functional granule docking to the plasma membrane

In regulated exocytosis, it is generally assumed that vesicles must stably “dock” at the plasma membrane before they are primed to become fusion-competent. However, recent biophysical analyses in living cells that visualize fluorescent secretory granules have revealed that exocytic behaviors are not...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Mizuno, Kouichi, Fujita, Takuji, Gomi, Hiroshi, Izumi, Tetsuro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817151/
https://ncbi.nlm.nih.gov/pubmed/27032672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23909
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