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Granuphilin exclusively mediates functional granule docking to the plasma membrane

In regulated exocytosis, it is generally assumed that vesicles must stably “dock” at the plasma membrane before they are primed to become fusion-competent. However, recent biophysical analyses in living cells that visualize fluorescent secretory granules have revealed that exocytic behaviors are not...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mizuno, Kouichi, Fujita, Takuji, Gomi, Hiroshi, Izumi, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817151/
https://ncbi.nlm.nih.gov/pubmed/27032672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23909
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