Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation

The monomeric small GTPase Rab27a is specifically localized on both secretory granules and lysosome-related organelles. Although natural mutations of the Rab27a gene in human Griscelli syndrome and in ashen mice cause partial albinism and immunodeficiency reflecting the dysfunction of lysosome-relat...

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Detalhes bibliográficos
Main Authors: Kasai, Kazuo, Ohara-Imaizumi, Mica, Takahashi, Noriko, Mizutani, Shin, Zhao, Shengli, Kikuta, Toshiteru, Kasai, Haruo, Nagamatsu, Shinya, Gomi, Hiroshi, Izumi, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546426/
https://ncbi.nlm.nih.gov/pubmed/15690086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522955
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