Nalaganje...
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation
The monomeric small GTPase Rab27a is specifically localized on both secretory granules and lysosome-related organelles. Although natural mutations of the Rab27a gene in human Griscelli syndrome and in ashen mice cause partial albinism and immunodeficiency reflecting the dysfunction of lysosome-relat...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546426/ https://ncbi.nlm.nih.gov/pubmed/15690086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522955 |
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