TIRF imaging of docking and fusion of single insulin granule motion in primary rat pancreatic β-cells: different behaviour of granule motion between normal and Goto–Kakizaki diabetic rat β-cells

We imaged and analysed the motion of single insulin secretory granules near the plasma membrane in live pancreatic β-cells, from normal and diabetic Goto–Kakizaki (GK) rats, using total internal reflection fluorescence microscopy (TIRFM). In normal rat primary β-cells, the granules that were fusing...

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Detalhes bibliográficos
Main Authors: Ohara-Imaizumi, Mica, Nishiwaki, Chiyono, Kikuta, Toshiteru, Nagai, Shintaro, Nakamichi, Yoko, Nagamatsu, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Accelerated Publication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133756/
https://ncbi.nlm.nih.gov/pubmed/15128287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040434
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