ELKS, a Protein Structurally Related to the Active Zone-associated Protein CAST, Is Expressed in Pancreatic β Cells and Functions in Insulin Exocytosis: Interaction of ELKS with Exocytotic Machinery Analyzed by Total Internal Reflection Fluorescence Microscopy

The cytomatrix at the active zone (CAZ) has been implicated in defining the site of Ca(2+)-dependent exocytosis of neurotransmitters. Here, we demonstrate the expression and function of ELKS, a protein structurally related to the CAZ protein CAST, in insulin exocytosis. The results of confocal and i...

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Auteurs principaux: Ohara-Imaizumi, Mica, Ohtsuka, Toshihisa, Matsushima, Satsuki, Akimoto, Yoshihiro, Nishiwaki, Chiyono, Nakamichi, Yoko, Kikuta, Toshiteru, Nagai, Shintaro, Kawakami, Hayato, Watanabe, Takashi, Nagamatsu, Shinya
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2005
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165411/
https://ncbi.nlm.nih.gov/pubmed/15888548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0816
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