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Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis
The mechanism of glucose-induced biphasic insulin release is unknown. We used total internal reflection fluorescence (TIRF) imaging analysis to reveal the process of first- and second-phase insulin exocytosis in pancreatic β cells. This analysis showed that previously docked insulin granules fused a...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064214/ https://ncbi.nlm.nih.gov/pubmed/17502420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608132 |
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