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Granuphilin Modulates the Exocytosis of Secretory Granules through Interaction with Syntaxin 1a
The molecular mechanism for the regulated exocytosis of dense-core granules in endocrine cells remains relatively uncharacterized compared to that of synaptic vesicles in neurons. A novel set of Rab and its effector, Rab27a/granuphilin, which is localized on insulin granules in pancreatic beta cells...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133943/ https://ncbi.nlm.nih.gov/pubmed/12101244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5518-5526.2002 |
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