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Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis
Exophilin8/MyRIP/Slac2-c is an effector protein of the small GTPase Rab27a and is specifically localized on retinal melanosomes and secretory granules. We investigated the role of exophilin8 in insulin granule trafficking. Exogenous expression of exophilin8 in pancreatic β cells or their cell line,...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093323/ https://ncbi.nlm.nih.gov/pubmed/21441305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-05-0404 |
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