Role of LRP1 in the pathogenesis of Alzheimer’s disease: evidence from clinical and preclinical studies

Among the LDL receptor (LDLR) family members, the roles of LDLR-related protein (LRP)1 in the pathogenesis of Alzheimer’s disease (AD), especially late-onset AD, have been the most studied by genetic, neuropathological, and biomarker analyses (clinical studies) or cellular and animal model systems (...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Shinohara, Mitsuru, Tachibana, Masaya, Kanekiyo, Takahisa, Bu, Guojun
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2017
Subjects:
Thematic Review Series
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496044/
https://ncbi.nlm.nih.gov/pubmed/28381441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075796
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