Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca(2+) entry regulates disassembly of adherens junctions

Vascular endothelial protein tyrosine phosphatase (VE-PTP) stabilizes endothelial adherens junctions (AJs) through constitutive dephosphorylation of VE-cadherin. Here we investigated the role of stromal interaction molecule 1 (STIM1) activation of store-operated Ca(2+) entry (SOCE) in regulating AJ...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Soni, Dheeraj, Regmi, Sushil C., Wang, Dong-Mei, DebRoy, Auditi, Zhao, You-Yang, Vogel, Stephen M., Malik, Asrar B., Tiruppathi, Chinnaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495943/
https://ncbi.nlm.nih.gov/pubmed/28385807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00008.2017
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