Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5

The recessive N-ethyl-N-nitrosourea–induced phenotype toku is characterized by delayed hair growth, progressive hair loss, and excessive accumulation of dermal cholesterol, triglycerides, and ceramides. The toku phenotype was attributed to a null allele of Gk5, encoding glycerol kinase 5 (GK5), a sk...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Duanwu, Tomisato, Wataru, Su, Lijing, Sun, Lei, Choi, Jin Huk, Zhang, Zhao, Wang, Kuan-wen, Zhan, Xiaoming, Choi, Mihwa, Li, Xiaohong, Tang, Miao, Castro-Perez, Jose M., Hildebrand, Sara, Murray, Anne R., Moresco, Eva Marie Y., Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495269/
https://ncbi.nlm.nih.gov/pubmed/28607088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705312114
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