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DNA-PKcs, Allostery, and DNA Double-Strand Break Repair: Defining the Structure and Setting the Stage

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is central to the regulation of the DNA damage response and repair through nonhomologous end joining. The structure has proved challenging due to its large size and multiple HEAT repeats. We have recently reported crystals of selenomethionine...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Methods Enzymol
मुख्य लेखकों: Chirgadze, Dimitri Y., Ascher, David B., Blundell, Tom L., Sibanda, Bancinyane L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495172/
https://ncbi.nlm.nih.gov/pubmed/28668119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.04.001
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