Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA

We recently identified pathogenic KIF1Bβ mutations in sympathetic nervous system malignancies that are defective in developmental apoptosis. Here we deleted KIF1Bβ in the mouse sympathetic nervous system and observed impaired sympathetic nervous function and misexpression of genes required for sympa...

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Опубликовано в: :Genes Dev
Главные авторы: Fell, Stuart M., Li, Shuijie, Wallis, Karin, Kock, Anna, Surova, Olga, Rraklli, Vilma, Höfig, Carolin S., Li, Wenyu, Mittag, Jens, Henriksson, Marie Arsenian, Kenchappa, Rajappa S., Holmberg, Johan, Kogner, Per, Schlisio, Susanne
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495120/
https://ncbi.nlm.nih.gov/pubmed/28637693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.297077.117
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