Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA

We recently identified pathogenic KIF1Bβ mutations in sympathetic nervous system malignancies that are defective in developmental apoptosis. Here we deleted KIF1Bβ in the mouse sympathetic nervous system and observed impaired sympathetic nervous function and misexpression of genes required for sympa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Fell, Stuart M., Li, Shuijie, Wallis, Karin, Kock, Anna, Surova, Olga, Rraklli, Vilma, Höfig, Carolin S., Li, Wenyu, Mittag, Jens, Henriksson, Marie Arsenian, Kenchappa, Rajappa S., Holmberg, Johan, Kogner, Per, Schlisio, Susanne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495120/
https://ncbi.nlm.nih.gov/pubmed/28637693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.297077.117
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