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Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression

Neuroblastoma is a pediatric cancer characterized by variable outcomes ranging from spontaneous regression to life-threatening progression. High-risk neuroblastoma patients receive myeloablative chemotherapy with hematopoietic stem-cell transplant followed by adjuvant retinoid differentiation treatm...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Westerlund, Isabelle, Shi, Yao, Toskas, Konstantinos, Fell, Stuart M., Li, Shuijie, Surova, Olga, Södersten, Erik, Kogner, Per, Nyman, Ulrika, Schlisio, Susanne, Holmberg, Johan
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544284/
https://ncbi.nlm.nih.gov/pubmed/28696319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700655114
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