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Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2 gene

BACKGROUND: Chromosomal instability is a hallmark of human cancer caused by errors in mitotic control and chromosome segregation. STAG2 encodes a subunit of the cohesion complex that participates in mitotic chromatid separation and was recently found to show low expression and inactivating mutations...

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Autori principali: Djos, Anna, Fransson, Susanne, Kogner, Per, Martinsson, Tommy
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853135/
https://ncbi.nlm.nih.gov/pubmed/24088605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-102
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