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The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

BACKGROUND: Hypermethylation of promotor CpG islands is a common mechanism that inactivates tumor suppressor genes in cancer. Genes belonging to the RASSF gene family have frequently been reported as epigenetically silenced by promotor methylation in human cancers. Two members of this gene family, R...

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Main Authors: Djos, Anna, Martinsson, Tommy, Kogner, Per, Carén, Helena
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493266/
https://ncbi.nlm.nih.gov/pubmed/22695170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-40
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