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The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

BACKGROUND: Hypermethylation of promotor CpG islands is a common mechanism that inactivates tumor suppressor genes in cancer. Genes belonging to the RASSF gene family have frequently been reported as epigenetically silenced by promotor methylation in human cancers. Two members of this gene family, R...

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Détails bibliographiques
Auteurs principaux: Djos, Anna, Martinsson, Tommy, Kogner, Per, Carén, Helena
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493266/
https://ncbi.nlm.nih.gov/pubmed/22695170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-40
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