Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

BACKGROUND: Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor suppressor gene and have been found to be important in several types of cancer. R...

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Main Authors: Kryh, Hanna, Carén, Helena, Erichsen, Jennie, Sjöberg, Rose-Marie, Abrahamsson, Jonas, Kogner, Per, Martinsson, Tommy
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178547/
https://ncbi.nlm.nih.gov/pubmed/21899760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-443
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