High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset

Analysis of chromosomal aberrations is used to determine the prognosis of neuroblastomas (NBs) and to aid treatment decisions. MYCN amplification (MNA) alone is an incomplete poor prognostic factor, and chromosome 11q status has recently been included in risk classification. We analyzed 165 NB tumor...

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Detalhes bibliográficos
Main Authors: Carén, Helena, Kryh, Hanna, Nethander, Maria, Sjöberg, Rose-Marie, Träger, Catarina, Nilsson, Staffan, Abrahamsson, Jonas, Kogner, Per, Martinsson, Tommy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840092/
https://ncbi.nlm.nih.gov/pubmed/20145112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910684107
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