Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling

Neuroblastoma (NB) is a childhood tumor that arises from the sympathoadrenal lineage. MYCN amplification is the most reliable marker for poor prognosis and MYCN overexpression in embryonic mouse sympathetic ganglia results in NB-like tumors. MYCN cooperates with mutational activation of anaplastic l...

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發表在:J Neurosci
Main Authors: Kramer, Marco, Ribeiro, Diogo, Arsenian-Henriksson, Marie, Deller, Thomas, Rohrer, Hermann
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705582/
https://ncbi.nlm.nih.gov/pubmed/27707976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0183-16.2016
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