Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts

Although tumor‐initiating cell (TIC) self‐renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we show that long‐term progression of PDAC in serial xenotranspla...

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Bibliografski detalji
Izdano u:EMBO Mol Med
Glavni autori: Ball, Claudia R, Oppel, Felix, Ehrenberg, Karl Roland, Dubash, Taronish D, Dieter, Sebastian M, Hoffmann, Christopher M, Abel, Ulrich, Herbst, Friederike, Koch, Moritz, Werner, Jens, Bergmann, Frank, Ishaque, Naveed, Schmidt, Manfred, von Kalle, Christof, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt, Weichert, Wilko, Weitz, Jürgen, Glimm, Hanno
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494525/
https://ncbi.nlm.nih.gov/pubmed/28526679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607354
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