Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts

Although tumor‐initiating cell (TIC) self‐renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we show that long‐term progression of PDAC in serial xenotranspla...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Ball, Claudia R, Oppel, Felix, Ehrenberg, Karl Roland, Dubash, Taronish D, Dieter, Sebastian M, Hoffmann, Christopher M, Abel, Ulrich, Herbst, Friederike, Koch, Moritz, Werner, Jens, Bergmann, Frank, Ishaque, Naveed, Schmidt, Manfred, von Kalle, Christof, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt, Weichert, Wilko, Weitz, Jürgen, Glimm, Hanno
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494525/
https://ncbi.nlm.nih.gov/pubmed/28526679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607354
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