Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G(0/1) phase

Ectopic viral integration site 1 (EVI1), a transcription factor frequently overexpressed in myeloid neoplasias, has been implicated in the generation of malignancy-associated centrosomal aberrations and chromosomal instability. Here, we sought to investigate the underlying cause of centrosome amplif...

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Bibliographic Details
Main Authors: Karakaya, Kadin, Herbst, Friederike, Ball, Claudia, Glimm, Hanno, Krämer, Alwin, Löffler, Harald
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467026/
https://ncbi.nlm.nih.gov/pubmed/22894935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21801
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