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A magic bullet for targeting cancers with supernumerary centrosomes

Centrosome amplification is frequently observed in aggressive human cancers, and it has been proposed as a promising target in cancer therapy. Work by Mariappan et al (2019) in this issue details the identification of a small‐molecule inhibitor that perturbs the CPAP–tubulin interaction, prevents ef...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Liu, Yi, Pelletier, Laurence
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331713/
https://ncbi.nlm.nih.gov/pubmed/30538103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101134
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