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DNA‐binding determinants and cellular thresholds for human telomerase repeat addition processivity

The reverse transcriptase telomerase adds telomeric repeats to chromosome ends. Purified human telomerase catalyzes processive repeat synthesis, which could restore the full ~100 nucleotides of (T(2) AG (3))(n) lost from replicated chromosome ends as a single elongation event. Processivity inhibitio...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Wu, Robert Alexander, Tam, Jane, Collins, Kathleen
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494469/
https://ncbi.nlm.nih.gov/pubmed/28495680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796887
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