Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA

Telomerase copies its internal RNA template to synthesize telomeric DNA repeats. Unlike other polymerases, telomerase can retain its single-stranded product through multiple rounds of template dissociation and repositioning to accomplish repeat addition processivity (RAP). Tetrahymena telomerase hol...

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Detalhes bibliográficos
Main Authors: Zeng, Zhixiong, Min, Bosun, Huang, Jing, Hong, Kyungah, Yang, Yuting, Collins, Kathleen, Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Telomerase and Retrotransposons: Reverse Transcriptases That Shaped Genomes Special Feature Sackler Colloquium
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251112/
https://ncbi.nlm.nih.gov/pubmed/22143754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113624108
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