Wird geladen...

The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro

In Saccharomyces cerevisiae, a Cdc13–Est1 interaction is proposed to mediate recruitment of telomerase to DNA ends. Here we provide unique in vitro evidence for this model by demonstrating a direct interaction between purified Cdc13 and Est1. The Cdc13–Est1 interaction is specific and requires the i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wu, Yun, Zakian, Virginia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251085/
https://ncbi.nlm.nih.gov/pubmed/21969561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100281108
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!