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DNA‐binding determinants and cellular thresholds for human telomerase repeat addition processivity
The reverse transcriptase telomerase adds telomeric repeats to chromosome ends. Purified human telomerase catalyzes processive repeat synthesis, which could restore the full ~100 nucleotides of (T(2) AG (3))(n) lost from replicated chromosome ends as a single elongation event. Processivity inhibitio...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494469/ https://ncbi.nlm.nih.gov/pubmed/28495680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796887 |
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