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Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex

With eukaryotic genome replication, incomplete telomere synthesis results in chromosome shortening and eventual compromise of genome stability. Telomerase counteracts this terminal sequence loss by synthesizing telomeric repeats through repeated cycles of reverse transcription of its internal RNA te...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wu, Robert Alexander, Collins, Kathleen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194115/
https://ncbi.nlm.nih.gov/pubmed/24619002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387205
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