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Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex
With eukaryotic genome replication, incomplete telomere synthesis results in chromosome shortening and eventual compromise of genome stability. Telomerase counteracts this terminal sequence loss by synthesizing telomeric repeats through repeated cycles of reverse transcription of its internal RNA te...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2014
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194115/ https://ncbi.nlm.nih.gov/pubmed/24619002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387205 |
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