The MYC mRNA 3′‐UTR couples RNA polymerase II function to glutamine and ribonucleotide levels

Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing “glutamine addiction”. Surprisingly, colon cancer cells that express high levels of MYC due to WNT pathway mutations are not glutamine‐addicted but undergo a reversible cell cycle...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Dejure, Francesca R, Royla, Nadine, Herold, Steffi, Kalb, Jacqueline, Walz, Susanne, Ade, Carsten P, Mastrobuoni, Guido, Vanselow, Jens T, Schlosser, Andreas, Wolf, Elmar, Kempa, Stefan, Eilers, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494468/
https://ncbi.nlm.nih.gov/pubmed/28408437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796662
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados