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MYC and tumor metabolism: chicken and egg

Transcription factors of the MYC family are deregulated in the majority of all human cancers. Oncogenic levels of MYC reprogram cellular metabolism, a hallmark of cancer development, to sustain the high rate of proliferation of cancer cells. Conversely, cells need to modulate MYC function according...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Dejure, Francesca R, Eilers, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709748/
https://ncbi.nlm.nih.gov/pubmed/29127156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796438
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