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The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance
Our recent study shows that the translation of MYC mRNA (mRNA) is controlled by its 3′ untranslated region (UTR) in a process that depends on the availability of glutamine and levels of cellular nucleotides. Metabolic feedback protects cells from a lethal glutamine addiction and may compromise metab...
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| 發表在: | Mol Cell Oncol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540213/ https://ncbi.nlm.nih.gov/pubmed/28868350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1338209 |
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