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Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail
Eukaryotic mRNAs possess a poly(A) tail that enhances translation via the (7)mGpppN cap structure or internal ribosome entry sequences (IRESs). Here we address the question of how cellular IRESs recruit the ribosome and how recruitment is augmented by the poly(A) tail. We show that the poly(A) tail...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491467/ https://ncbi.nlm.nih.gov/pubmed/18556416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1043908 |
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