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Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay
In eukaryotes, a surveillance pathway known as nonsense-mediated decay (NMD) regulates the abundance of messenger RNAs containing premature termination codons (PTCs). In mammalian cells, it has been asserted that the NMD-relevant first round of translation is special and involves initiation by a spe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500827/ https://ncbi.nlm.nih.gov/pubmed/16799467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400721 |
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