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The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD)
Platelet production is induced by the cytokine thrombopoietin (TPO). It is physiologically critical that TPO expression is tightly regulated, because lack of TPO causes life-threatening thrombocytopenia while an excess of TPO results in thrombocytosis. The plasma concentration of TPO is controlled b...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458284/ https://ncbi.nlm.nih.gov/pubmed/16679454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl277 |
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