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Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation

Numerous cellular mRNAs encoding proteins critical during cell stress, apoptosis, and the cell cycle seem to be translated by means of internal ribosome entry sequences (IRES) when cap-dependent translation is compromised. The underlying molecular mechanisms are largely unknown. Using a HeLa-based c...

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Détails bibliographiques
Auteurs principaux: Hundsdoerfer, Patrick, Thoma, Christian, Hentze, Matthias W.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224658/
https://ncbi.nlm.nih.gov/pubmed/16174738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506536102
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