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IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry

Translation of the genomes of several positive-sense RNA viruses follows end-independent initiation on an internal ribosomal entry site (IRES) in the viral mRNA. There are four major IRES groups, and despite major differences in the mechanisms that they use, one unifying characteristic is that each...

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Detalhes bibliográficos
Autor principal: Hellen, Christopher U.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935204/
https://ncbi.nlm.nih.gov/pubmed/19539793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2009.06.001
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